Asked enough times this past year to do a quick stack. Standard caveats: not a clinician, not a strength coach, ABD in neuro — please use this as a starting point for your own reading, not as advice.
Daily, all evidence-supported and modestly priced:
- Creatine monohydrate 5g (the only supplement I'd defend in a debate)
- Vitamin D3 2000 IU in winter, dropped to 1000 IU in summer (last 25(OH)D was 22, NE winters)
- Magnesium glycinate 300mg before bed (sleep, not muscle — and the GI tolerance is the reason for glycinate)
- Omega-3 (EPA+DHA) ~1g/day (modest cardiovascular evidence; I'd skip if you eat fatty fish 2-3x/week)
Things I do *not* take and frequently get asked about: ashwagandha (sleep evidence is okay but liver case reports give me pause at the doses people use), berberine (signal is real but it interacts with too many things to recommend casually), NAD+ precursors (the human data does not match the marketing).
If you're starting from zero — D3 + creatine + the omega-3 if your diet warrants it. That covers 90% of what most people would benefit from. The rest is at the margin.
Last note: a daily multivitamin is not on this list. The evidence does not support routine multi use in healthy adults eating a varied diet. If your diet is bad, fix the diet — the multi won't save you.
Asked enough times this past year to do a quick stack. Standard caveats: not a clinician, not a strength coach, ABD in neuro — please use this as a starting point for your own reading, not as advice.
Daily, all evidence-supported and modestly priced:
- Creatine monohydrate 5g (the only supplement I'd defend in a debate)
- Vitamin D3 2000 IU in winter, dropped to 1000 IU in summer (last 25(OH)D was 22, NE winters)
- Magnesium glycinate 300mg before bed (sleep, not muscle — and the GI tolerance is the reason for glycinate)
- Omega-3 (EPA+DHA) ~1g/day (modest cardiovascular evidence; I'd skip if you eat fatty fish 2-3x/week)
Things I do *not* take and frequently get asked about: ashwagandha (sleep evidence is okay but liver case reports give me pause at the doses people use), berberine (signal is real but it interacts with too many things to recommend casually), NAD+ precursors (the human data does not match the marketing).
If you're starting from zero — D3 + creatine + the omega-3 if your diet warrants it. That covers 90% of what most people would benefit from. The rest is at the margin.
Last note: a daily multivitamin is not on this list. The evidence does not support routine multi use in healthy adults eating a varied diet. If your diet is bad, fix the diet — the multi won't save you.